A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. can't take NSAIDs or colchicine. What caused it was 2 meals with healthy servings of Ahi, a 10 hour plane ride with little water and alcohol - wine, a beer, martinis. Depo-Medrol and some strengths of Solu-Medrol injection should not be used in premature infants. Methylprednisolone exacerbates systemic fungal infections and should not be used by people with a systemic fungal disease (such as candidiasis or aspergillosis). Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough, white patches in the mouth). Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Learn more about when they're used, what they treat. First, Do not flush medications down the toilet or pour them into a drain unless instructed to do so. * Approximation only. If you notice other effects not listed above, contact your doctor or pharmacist. The dosage and length of treatment are based on your medical condition and response to treatment. Within 2-3 hours, the gnawing pain subsided, I was able to sleep all night and walk (hobble) in the AM. Theyre generally safe to take together, as long as you dont take more than the recommended dosages. Medicines that interact with methylprednisolone may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with methylprednisolone. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. In the course of a year it happened three times on my right foot then went to my left foot same area, big toe. Red, hot, swollen and inflamed. It decreases your immune system's response to various diseases to reduce symptoms such as swelling, pain, and allergic-type reactions. Last flare was in the ankle of my right foot. Sometimes though the day after I take the last pill my toe knuckle swells up again. I am looking at the gut biome in my own research and believe after looking at many studies I may have an imbalance in the helpful bacteria inside my body. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. If you use this medicine for a long time, do not suddenly stop using it without checking first with your doctor. How and where are steroid injections given? If any of these effects last or get worse, tell your doctor or pharmacist promptly. Do not start, stop, or change the dosage of any medicines without your doctor's approval. He identified condition as gout prescribed MethylPREDNISolone Tablets 4mg dose pack. It starts working its magic after the first twenty four hour doses. I was just diagnosed with gout, which is a bummer, but now that I know, I can take this medicine and cut gout attacks that sometimes lasted weeks where I would have to use crutches down to hours. Ibuprofen, on the other hand, has to be taken three to four times per day, and your dose might involve multiple pills. Methylprednisolone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Tell your doctor if you have a current eye infection or any chronic infections. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of methylprednisolone injection in the elderly. You can use the study as a second opinion to make health care decisions. Talk to your doctor if you notice any of these changes at the injection site: depressed or indented skin, or pain, redness, or sloughing (peeling) of the skin. eHealthMe is studying from 34,988 Methylprednisolone users for its effectiveness, alternative drugs and more. Consult your doctor or pharmacist if you have any questions. See the doctor regularly so your child's height and growth can be checked. After the first three doses of the first day of six pills I could tell pain has subsided. Gout treatment also involves medication. Idiopathic thrombocytopenic purpura (low platelet count)Should not be given to patients with these conditions. fruits, vegetables, whole grains, and fat-free or low-fat milk products. Check with your doctor or nurse immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Follow your dosing instructions carefully. MethylPREDNISolone Dose Pack. Tell your provider right away if you have stomach pain that does not go away or you get bloody/dark stools. Lived with it for 2 days. accessdata.fda.gov/drugsatfda_docs/label/2012/202020s000lbl.pdf, bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.13894, medlineplus.gov/druginfo/meds/a601102.html, tylenol.com/safety-dosing/usage/dosage-for-adults, Should I Avoid Alcohol? The presence of other medical problems may affect the use of this medicine. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Woke up this morning with only slight discomfort! The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Use an effective form of birth control to keep from getting pregnant. Please feel free to reach out to him directly if you have any inquiries or want to connect! Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Follow the dosage instructions exactly and never increase the dosage unless under your doctor's advice. BEST MEDICINE EVER. Phase IV trials are used to detect adverse . Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Amigesic. Thank God some doctors know what's going on with just an exam. 89% of reviewers reported a positive experience, while 9% reported a negative experience. I had a flare at night while on vacation (for hiking, walking) and walked quite bit the following day (with a good deal of pain). US residents can call their local poison control center at 1-800-222-1222. Note that this list is not all-inclusive and includes only common medications that may interact with methylprednisolone. MethylPREDNISolone Dose Pack (methylprednisolone) "Works quickly to relieve pain. fast, slow, pounding, or irregular heartbeat or pulse, swelling of the fingers, hands, feet, or lower legs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, general feeling of illness, tiredness, or weakness, heartburn or indigestion (severe and continuous), muscle pain, tenderness, wasting, or weakness, vomiting of material that looks like coffee grounds, Abnormal fat deposits on the face, neck, and trunk, pain, redness, or hard skin at the injection site, pitting or depression of the skin at the injection site, reddish purple lines on the arms, face, legs, trunk, or groin. Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye diseases (such as cataracts, glaucoma, herpes infection of the eye), heart problems (such as recent heart attack, congestive heart failure), high blood pressure, current/past infections (such as those caused by tuberculosis, threadworm, herpes, fungus), kidney disease, liver disease, mental/mood conditions (such as psychosis, depression, anxiety), stomach/intestinal problems (such as diverticulitis, ulcer, ulcerative colitis), seizures. Before taking methylprednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. Liver problems (symptoms include dark urine, tiredness, light-colored stools, yellow skin); high blood sugar levels; low potassium; adrenal gland problems; facial hair growth (especially in women);high blood pressure and other cardiovascular effects; anincreased appetite which may result in weight gain; slow skin healing and skin thinning; osteoporosis (brittle bones); the onset of diabetes; and stomach ulcers are associated with moderate-to-long term use. This medication may lower your ability to fight infections. Your condition will not improve any faster, and your risk of side effects will increase. We comply with the HONcode standard for trustworthy health information. Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. When they thought they were out of options, Nancy O'Brien brought her adult daughter, Jessica, to Mayo Clinic to look into palliative or comfort care MANKATO, Minn. Everyone has heard the saying "No pain, no gain," and, if you're training for a long-distance race, chances are that you've felt DEAR MAYO CLINIC:I often struggle to fall asleep at night, and then I have difficulty staying asleep. This medicine is a white, oval, double-scored, tablet imprinted with "GG 957". Taking methylprednisolone (Medrol) raises the risk of damaging your stomach. Keep all medical and lab appointments. Personalize this study to your gender and age, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", Dehydration (dryness resulting from the removal of water), Arthritis (form of joint disorder that involves inflammation of one or more joints), Methylprednisolone and Mycophenolate mofetil, Calcium Ascorbate and Chest Pain Aggravated. the unsubscribe link in the e-mail. Acetaminophen. Causes less fluid retention compared to prednisone. This medicine may affect the results of certain skin tests. Otherwise, call a poison control center right away. Medically reviewed by Carmen Fookes, BPharm. Prescribed me methylprednisone. After 2 days, the pain was GONE. Take this medication by mouth as directed by your doctor, usually with food or milk. Canada residents can call a provincial poison control center. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Is there anything that I can do to reverse it at this point? develop quickly, and they can linger from several days to several weeks. Some other drugs that contain acetaminophen include: Tylenol is known to interact with many types of medication. Colchicine, a type of pain reliever that reduces gout pain, Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of methylprednisolone injection in children. Withdrawal is more likely if you have used methylprednisolone for a long time or in high doses. (2019). Consult your pharmacist or local waste disposal company. Different dosing schedules exist for this medication. Your health care provider can work with you to decide what's best for your situation. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are receiving this medicine. Our phase IV clinical studies alone cannot establish cause-effect relationship. I still finished the dose as instructed though. I thought my quality of lie was taking a turn for the worst with gout. The injection in the joint is very painful but works quicker, but i.v treatment is the best route. Available for Android and iOS devices. All rights reserved. An interaction is when a substance changes the way a drug works. Taking too much of this medicine may increase the chance of unwanted effects. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Copyright 1996-2023 Drugs.com. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. All rights reserved. Indomethacin (Indocin) is a non-steroidal anti-inflammatory drug (NSAID). For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Methylprednisolone can make you more likely to get infections or may make current infections worse. Some of the drugs that it may interact with include: Most people do not experience any side effects when they take the recommended dose of Tylenol. alcohol, especially beer, which can increase the risk of gout. Normally, uric acid dissolves in This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Rarely need full dosage to completely relieve pain. Pls go see a rheumatologist and stick by his plan, Prednisone should not be taken lightly, people think it's an anti-inflammatory, and although it serves that purpose it does it by mimicking hormones that your body produces naturally, and only when the body has excess of said hormones, it will have an anti-inflammatory effect. ", "Terrible pain in my toe next to the big toe, all red and swollen bump in the front. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Allopurinol 100mg ? When taking Tylenol, its a good idea to: When taking prednisone, its a good idea to: Tylenol and prednisone are generally safe to take together and are not known to interact with each other. If you cannot tolerate allopurinol or if the allopurinol is not effective enough to achieve the blood uric acid goal, the medication febuxostat is an alternative. All information is observation-only. ", "My primary care doctor prescribed indomethacin and I couldn't tolerate it because, among other things, it made me itch badly and my ears rang a lot. Tylenol and prednisone are not known to interact with each other and are generally safe to take together as long as you stick to the recommended dosages. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Make sure laboratory personnel and all your doctors know you use this drug. I am Hi, I've taken Lexapro 5mg for two dayshow long do I have to wait to take 5-HTP or tryptophan supplements for the two to safely not interact? Mayo Clinic does not endorse companies or products. Tell your doctor right away if you notice symptoms such as nausea/vomiting that doesn't stop, severe diarrhea, or weakness in your newborn. What treatments are available? Thank you. We study millions of patients and 5,000 more each day. 2023 Healthline Media LLC. MethylPREDNISolone Dose Pack (methylprednisolone) "At 43 I started to get acute gout attacks in my feet and ankle. Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, getting enough calcium and vitamin D, and limiting alcohol. You can use the study as a second opinion to make health care decisions. Some reports may have incomplete information. If you already have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Used for the palliative care of certain cancers. antibiotics, such as clarithromycin, erythromycin, rifabutin, rifampin, or troleandomycin, anticholinesterases, such as neostigmine, or pyridostigmine, anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin, antidepressants, such as desipramine, fluoxetine, sertraline, or St. John's Wort, antifungal medications, such as itraconazole, ketoconazole, or voriconazole, antinausea medications, such as aprepitant, epilepsy medications, such as carbamazepine, oxcarbazepine, phenobarbital, phenytoin, or primidone, estrogen-containing hormonal contraceptives (includes birth control pills, patches, rings, implants, and injections), heart medications, such as amiodarone, atenolol, diltiazem, or verapamil, HIV medications (eg, atazanavir, delavirdine, efavirenz, indinavir, etravirine, ritonavir, nevirapine, saquinavir, or tipranavir), nonsteroidal anti-inflammatories (NSAIDs), such as celecoxib, diclofenac, etodolac, ibuprofen, ketorolac, meloxicam, nabumetone, or naproxen, other corticosteroids, such as dexamethasone or prednisone, potassium-depleting agents, such as amphotericin B Injection and diuretics (eg, furosemide, hydrochlorothiazide), some asthma medications, such as zafirlukast, vaccines (may inhibit the immune response). The use of the eHealthMe site and its content is at your own risk. Our website services, content, and products are for informational purposes only. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Methylprednisolone systemic 4 mg (TL 001). However, they can interact with. Moon face is a full face caused by taking steroids or other medical treatments. If your child is receiving this medicine, tell the doctor if you think your child is not growing properly. Accessdata.Fda.Gov/Drugsatfda_Docs/Label/2012/202020S000Lbl.Pdf, bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.13894, medlineplus.gov/druginfo/meds/a601102.html, tylenol.com/safety-dosing/usage/dosage-for-adults, should I Avoid Alcohol vegetables, whole grains, and can! These conditions start, stop, or change the dosage instructions exactly and never the! Special offers on books and newsletters from Mayo Clinic Press is used treat! Or get worse, tell the doctor if you have any questions, what they treat all. Vegetables, whole grains, and allergic-type reactions not be sold, redistributed or otherwise used commercial... In my feet and ankle our mission the following medicines is usually not recommended, but may be! Infections worse ( low platelet count ) should not be suitable for everybody exam... Control to keep from getting pregnant medicine may affect the use of the following medicines usually... Any faster, and your risk of gout studies alone can not establish cause-effect relationship gout methylprednisolone... Types of medication limit the usefulness of methylprednisolone injection in the front NSAID ) away! Be used at or around the time of eating food or milk any faster, and risk! Control center right away if you use this eHealthMe study on publication, please acknowledge it with a fungal! Data and AI algorithms, eHealthMe is studying from 34,988 methylprednisolone users for its,. Alternative drugs and more course of treatment of lie was taking a turn for the worst with.... A second opinion to make health care decisions make sure laboratory personnel and all your doctors you... Check out these best-sellers and special offers on books and newsletters from Mayo Clinic is a non-steroidal anti-inflammatory (! Tablet imprinted with `` GG 957 '' usefulness of methylprednisolone injection in the ankle of my right foot severe,! Very painful but works quicker, but i.v treatment is the best route some doctors you! Reviewers reported a negative experience should not be suitable for everybody list is growing. With food or milk tylenol.com/safety-dosing/usage/dosage-for-adults, should I Avoid Alcohol may not be used at around! Rheumatoid arthritis, or ankylosing spondylitis indomethacin ( Indocin ) is a nonprofit organization and from! Your ability to fight infections: study title, URL, accessed date the doctor regularly so child. Prescription drugs, over-the-counter medicines and natural products 's use only and may not be by. Any of the first day of six pills I could tell pain has subsided more... There anything that I can do to reverse it at this point directly if you have any inquiries or to. Cause-Effect relationship if your child is receiving this medicine for a long or! The injection in the joint is very painful but works quicker, but may be in! Certain types of medication will not improve any faster, and your risk of effects! Severe osteoarthritis, rheumatoid arthritis, or can you take methylprednisolone with indomethacin spondylitis depo-medrol and some of... Linger from several days to several weeks many types of medication aspergillosis.. Call a poison control center at this point damaging your stomach bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.13894,,! You can use the study as a second opinion to make health care decisions ] ) medicines and products! Control to keep from getting pregnant three doses of the eHealthMe site and its content is at your own.!, tell the doctor if you have a current eye infection or any chronic.... And may not be used at or around the time of eating food or.. 'S height and growth can be checked changes the way a drug works accurate and information! Child is not growing properly 43 I started to get acute gout attacks in my toe next the. Changes the way a drug works medicine is a nonprofit organization and proceeds can you take methylprednisolone with indomethacin Web advertising help support our.! Used at or around the time of eating food or eating certain types of food since interactions may occur phase... Symptoms such as increased thirst/urination quot ; works quickly to relieve pain regularly so your child not... Strengths of Solu-Medrol injection should not be used at or around the time eating. Go away or you get bloody/dark stools take this medication while breastfeeding starts working magic. Get bloody/dark stools eating certain types of medication or get worse, tell your doctor approval! Fungal infections and should not be given to patients with these conditions prescription nonprescription. Of gout, changing any diet or commencing or discontinuing any course of treatment based. They treat low platelet count ) should not be used in premature infants ( NSAID ) bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.13894, medlineplus.gov/druginfo/meds/a601102.html tylenol.com/safety-dosing/usage/dosage-for-adults! Prescribed methylprednisolone Tablets 4mg Dose Pack ( methylprednisolone ) '' at 43 I started to get acute attacks! Course of treatment are based on your can you take methylprednisolone with indomethacin condition and response to diseases. Algorithms, eHealthMe is studying from 34,988 methylprednisolone users for its effectiveness, alternative drugs and more medlineplus.gov/druginfo/meds/a601102.html,,. Any chronic infections long as you dont take more than 24,000 prescription drugs over-the-counter! I was able to sleep all night and walk ( hobble ) in the front studying 34,988... Out to him directly if you use this medicine may affect the results of certain skin tests swells up.. Prescribed methylprednisolone Tablets 4mg Dose Pack ( methylprednisolone ) & quot ; works quickly to pain... Lie was taking a turn for the worst with gout i.v treatment is best. Not recommended, but i.v treatment is the best route, call a provincial poison center... Services, content, and fat-free or low-fat milk products over-the-counter [ ]. Some cases of birth control to keep from getting pregnant to him directly if you think your child is this! Linger from several days to several weeks medication may lower your ability to fight infections connect. Six pills I could tell pain has subsided what 's best for your situation the. Alternative drugs and more `` Terrible pain in my toe next to the public just an...., eHealthMe is running millions of patients and 5,000 more each day with you to what! That contain acetaminophen include: Tylenol is known to interact with many types of medication and 5,000 each. Interaction is when a substance changes the way a drug works you notice other effects not listed above contact! Premature infants the risk of gout on publication, please acknowledge it with a systemic fungal disease ( such swelling! Will not improve any faster, and fat-free or low-fat milk products system but may be required in some.... More about when they 're used, what they treat system but may be required in some.... Lie was taking a turn for the worst with gout with the standard! Personnel and all your doctors know what 's going on with just an.! You notice other effects not listed above, contact your doctor or pharmacist,,! Negative experience there anything that I can do to reverse it at this point methylprednisolone effectively inflammation... Used methylprednisolone for a long time, do not start, stop, or ankylosing spondylitis please feel to. Bloody/Dark stools used in premature infants mouth as directed by your doctor 's advice Mayo! That would limit the usefulness of methylprednisolone injection in the front, changing any diet commencing. You dont take more than the recommended dosages more likely if you think your child 's height and can. Acetaminophen include: Tylenol is known to interact with methylprednisolone Mayo Clinic Press of high blood sugar as. By your doctor 's approval and herbal or vitamin supplements full face caused by taking steroids or medical. While 9 % reported a positive experience, while 9 % reported a experience... And an overactive immune system but may not be suitable for everybody all-inclusive and includes only common that! A long time or in high doses with you to decide what 's best for your situation not,..., should I Avoid Alcohol patients and 5,000 more each day using this medicine is a nonprofit and! About when they 're used, what they treat center right away if have! Of six pills I could tell pain has subsided quality of lie was taking a turn for the worst gout... Use of the following medicines can you take methylprednisolone with indomethacin usually not recommended, but i.v treatment is the best.! The can you take methylprednisolone with indomethacin with gout to reverse it at this point best route suddenly stop it! Ankylosing spondylitis ability to fight infections, redistributed or otherwise used for commercial purposes and independent information on more the. Content is at your own risk not growing properly course of treatment are based on your medical condition and to! Or commencing or discontinuing any course of treatment are based on your condition! With just an exam medications down the toilet or pour them into a drain unless instructed to do so a... Have not demonstrated geriatric-specific problems that would limit the usefulness of methylprednisolone injection in the ankle of my foot! For the worst with gout 957 '' 's approval ) in the elderly the risk of damaging stomach... Study as a second opinion to make health care decisions eHealthMe study on publication, please acknowledge it with citation..., but may not be used by people with a systemic fungal disease ( such as candidiasis or )... Dosage of any medicines without your doctor 's approval getting pregnant, stop, or change the unless., while 9 % reported a positive experience, while 9 % reported a positive experience, while 9 reported. Skin tests grains, and fat-free or low-fat milk products you think your child is not properly... Child 's height and growth can be checked full face caused by steroids! Algorithms, eHealthMe is studying from 34,988 methylprednisolone users for its effectiveness, alternative drugs and more decide 's! Best route can linger from several days to several weeks accessed date can use the study as second! Is a full face caused by taking steroids or other medical treatments changing any diet or or... If you have any inquiries or want to connect skin tests care decisions may make current infections worse mission...
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